|May 2006 · Vol. 18, No. 5
Management of lupus flare
If disease is handled quickly, mother and fetus usually fare well, but loss of mother, fetus, or both is not always avoidable
It is impossible to predict who will have a lupus flare, when, and to what level of severity
Pregnancy termination doesn’t necessarily ameliorate lupus flare
OBG Management Board of Editors, Professor and Chairman, Department of Obstetrics and Gynecology, Penn State University College of Medicine, Obstetrician-Gynecologist-In-Chief, Milton S. Hershey Medical Center, Hershey, Pa
It was not that long ago that systemic lupus erythematosus (SLE) was considered a contraindication to pregnancy. With improved understanding and improved treatment options, many women with SLE have successful pregnancies.
Still, lupus flare during pregnancy is a medical and obstetric emergency, and a persistent obstetric dilemma. The most difficult dilemma is how to differentiate a lupus flare from preeclampsia, as both may present with worsening blood pressure, proteinuria and deteriorating renal function, and edema.1