|July 2010 · Vol. 22, No. 07
SECOND OF 2 PARTS
When treating interstitial cystitis,
address all sources of pain
Dietary modification, oral and intravesical agents, and even physical therapy may be necessary to render the pain of interstitial cystitis and painful bladder syndrome manageable
Although dimethylsulfoxide has very low systemic toxicity, it has proved to be teratogenic in animal studies
Amitriptyline is the tricyclic antidepressant most commonly prescribed for interstitial cystitis and painful bladder syndrome
Intravesical administration of local anesthetic agents such as lidocaine appears to provide significant relief from pelvic pain arising from interstitial cystitis and painful bladder syndrome
Dr. Howard is Professor and Associate Chair of the Department of Obstetrics and Gynecology, University of Rochester School of Medicine and Dentistry, Rochester, NY, where he also directs the Division of GYN Specialties.
Dr. Howard is a speaker and consultant for Ortho Women’s Health and Urology and a consultant for Ethicon Women’s Health and Urology.
In Part 1 of this article, I discussed an actual case of interstitial cystitis and painful bladder syndrome (IC/PBS) that was diagnosed in our clinic. That diagnosis was challenging, made over a period longer than 1 year. Regrettably, such a delay is not unusual—especially in patients who already have another diagnosis, such as endometriosis, as was true in that case.