October 2008 · Vol. 20, No. 10Fetal thrombophilia, perinatal stroke, and novel ideas about CP
Recent research findings point to thrombophilia and to stroke before or right after birth as one more basis for cerebral palsy. But can the knowledge make a difference in outcome?
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Fast Track
A mother whose baby has been given a diagnosis of thrombophilia and fetal or neonatal stroke can be offered thromboprophylaxis during any subsequent pregnancy
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Caroline
L.
Stella,
MDDr. Stella is a Fellow in the Division of Maternal–Fetal Medicine at the University of Cincinnati College of Medicine, Cincinnati, Ohio. Helen
Y.
How,
MDDr. How is a Professor in the Division of Maternal–Fetal Medicine at the University of Cincinnati College of Medicine, Cincinnati, Ohio. Baha
M.
Sibai,
MDDr. Sibai is a Professor in the Division of Maternal–Fetal Medicine at the University of Cincinnati College of Medicine, Cincinnati, Ohio.
The authors report no financial relationships relevant to this article.
Thrombosis is hypothesized to be the more common mechanism underlying cerebral palsy in many cases of maternal or fetal thrombophilia; for that reason, understanding the impact of maternal and fetal thrombophilia on pregnancy outcome is of paramount importance when counseling patients.
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