|July 2008 · Vol. 20, No. 07
UPDATE: ENDOMETRIAL CANCER
Clear guidelines are lacking on the assessment of lymphatic dissemination and on the anatomic extent of this assessment
Women undergoing lymphatic assessment for endometrial cancer should undergo full systematic lymph-node dissection, not sampling
Women who have advanced or recurrent endometrial cancer should receive chemotherapy with doxorubicin, cisplatin, and paclitaxel or a platinum taxane regimen
Dr. Mutch is the Judith and Ira C. Gall Professor and Director of the Division of Gynecologic Oncology at Washington University in St. Louis.
Dr. Rimel is a Fellow in the Division of Gynecologic Oncology of the Department of Obstetrics and Gynecology at Washington University in St. Louis.
The authors report no financial relationships relevant to this article.
Postmenopausal bleeding is a symptom evaluated often by general gynecologists. It necessitates assessment of the endometrium, most often by tissue sampling. When endometrial cancer is confirmed by biopsy, management becomes complex. Should the patient be referred to a gynecologic oncologist? What kind of surgery does she need? What kind of adjuvant treatment will be offered? Could the diagnosis be part of a genetic cancer syndrome?