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December 2006 · Vol. 18, No. 12

Noninvasive vulvar lesions:
An illustrated guide to diagnosis
and treatment

Dystrophies, vulvodynia, and other noncancerous lesions


Fast Track

Vulvar dystrophies

  • Lichen sclerosus

  • Squamous cell hyperplasia
    Formerly “hyperplastic dystrophy”

  • Other dermatosis

  • Squamous cell carcinoma in situ
    May present clinically at any age as papules or macules, coalescent or discrete, single or multiple

  • Paget’s disease of the vulva
    Clinicopathologic entity with a pathognomonic histologic appearance

    Source: Modified from Voet RL1

There is no good evidence that women with lichen sclerosus face a higher risk for vulvar carcinoma

Vulvodynia pain may never subside completely

Hallmark of vestibulitis: Severe pain on touch, with tenderness localized within the vestibule in a horseshoe pattern

VIN lesions are hyper- or pseudopigmented in about 30% of cases

Biopsy is essential for correct diagnosis of vulvar intraepithelial neoplasia

Paget’s disease of the vulva often recurs, especially when the initial lesion is large

IN THIS ARTICLE

Philip  J.  DiSaia,  MD

Professor and Director, Division of Gynecologic Oncology, Dorothy Marsh Chair in Reproductive Biology, University of California, Irvine

Dr. DiSaia is also Chairman of the Gynecologic Oncology Group and Past President and Chairman of the Board of the American Board of Obstetrics and Gynecology

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