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February 2006 · Vol. 18, No. 2

UPDATE on FERTILITY

New Developments that are Changing Patient Care

FERTILITY

Fast Track

I use metformin as first-line therapy in all women with confirmed PCOS, regardless of the reason for therapy

John  F.  Randolph  Jr,  MD

Professor and Director,
Reproductive Endocrinology and Infertility,
Obstetrics and Gynecology Dept.,
University of Michigan Health System,
 Ann Arbor

It seems that most advances in the field of infertility entail high-tech, high-risk therapies and expensive diagnostics that are the domain of subspecialists. But this year brought compelling evidence of a better “low-tech” treatment for a common dilemma that has challenged generalists and subspecialists alike for decades: PCOS-related infertility.

A more effective primary-care based strategy is all the more welcome because the difficulties encountered in helping women with PCOS achieve pregnancy have prompted many generalists to routinely refer these patients to subspecialty care.

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