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March 2005 · Vol. 17, No. 3

PART 2 OF 3

BEST PRACTICES FOR DIAGNOSIS AND MANAGEMENT OF PREECLAMPSIA

Expectant management of preeclampsia

How to maintain the precarious balance between fetal benefit and maternal health according to disease severity and gestational age.


IN THIS ARTICLE

Fast Track

Criteria for mild preeclampsia

  • 140-159 mm Hg systolic or 90-109 mm Hg diastolic on 2 occasions, 6 hours apart

  • Proteinuria 0.3-4.9 g in 24 hours

In mild preeclampsia, antihypertensive drugs may mask disease progression

In severe disease, expectant management is warranted only between 23 and 32 weeks, and only if mother and fetus are stable

Use calcium-channel blockers to control blood pressure in pregnant women with diabetes

Lowering blood pressure too rapidly during labor can reduce maternal organ perfusion, including uteroplacental blood flow

Start ACE inhibitors immediately postpartum in women with vascular diabetes or diabetic nephropathy

Baha  M.  Sibai,  MD

Professor and Chairman,
Department of Obstetrics and Gynecology, University of Cincinnati College of Medicine

Once you decide to expectantly manage a patient with preeclampsia, the balancing act begins. That means weighing fetal benefits against maternal risks, since the only justification for expectant management is to prolong pregnancy for fetal gain—there is no advantage to the mother.

The best approach is to classify the woman’s preeclampsia by the degree of severity and gestational age at the time of diagnosis, then follow recommendations tailored to that particular category.

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