|October 2012 · Vol. 24, No. 10
EXAMINING THE EVIDENCE
Does maternal exposure toYes. Maternal exposure is associated with a lower fetal heart-rate baseline (within the accepted normal range), decreased variability, and fewer prolonged decelerations—but there is no evidence of adverse effects on neonatal outcomes, according to this 4-year retrospective cohort study.EXPERT COMMENTARY
magnesium sulfate affect
fetal heart-rate patterns?
Hugh McAllister Distinguished Professor of Obstetrics and Gynecology at the University of North Carolina at Chapel Hill.
In contemporary obstetrics, electronic fetal monitoring (EFM) is used almost universally, and magnesium sulfate often is administered for seizure prophylaxis, tocolysis, or preterm neuroprotection. Given that magnesium crosses the placenta and is known to have both neurologic and cardiac effects and toxicities, it has been speculated that magnesium sulfate may change various characteristics of the fetal heart rate (FHR). Previous studies in small animals have failed to answer this common clinical question.
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