What are you waiting for?
Studies have proven that
Down syndrome screening is most effective
in the First Trimester
• Free Beta hCG/PAPP- A/ NT
• 91% detection at a 5% false positive rate
• All in the first trimester
• 95% of patients get earliest reassurance
• Aneuploidy screening completed early
• Allows for more time/diagnostic options
• Increases patient privacy, options
• Allows greater focus on the positive
aspects of pregnancy
For More Information Contact
NTD Laboratories, Inc.
The Prenatal Screening Specialists
1-888-NTD-LABS www.NTDLABS.com Fax (631) 425-0811
SCREENING BEYOND THE FIRST TRIMESTER: THE DRAWBACKS
INCREASED FALSE POSITIVES
First trimester screening followed by second
trimester screening interpreted independently
(i.e., sequential screening) leads to an unacceptably
high false positive rate (11% in the FASTER Trial).
When final screening results are delayed until
completion of second trimester screening, the
advantages of first trimester screening are lost.
Patient autonomy and privacy are also
Providing patients with two or more Down
syndrome results may lead to discrepant results that
are difficult to explain to patients and cause
Difficulties in coordinating results from blood tests
obtained in two different trimesters and from
different labs could lead to increased possibility for
errors. Additionally, 12% of patients in the FASTER
study did not return for the second trimester screen.
NTD OBGM 11/16/05 10:54 AM Page 1
Contact: NTD Laboratories
Phone: 1 888 ntd labs
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