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SRM | A clinical publication of the American Society for Reproductive Medicine

Endometriomas Don't Affect IVF Response Rates

Research suggests that removing endometriomas prior to in vitro fertilization may be unnecessary

(HealthDay News) - In women with endometriosis who undergo in vitro fertilization, the presence of endometriomas does not affect either the success rate of ovulation induction or the pregnancy rate, according to research presented this week at the 64th Annual Meeting of the American Society of Reproductive Medicine in San Francisco.

Stanley Jaffe, of the New York-Presbyterian/Weill Cornell Medical Center in New York City, and colleagues studied 586 patients with endometriosis who were scheduled to undergo in vitro fertilization in 2004-2005, including 104 (17.7 percent) who had endometriomas during the stimulation cycle, 86 (82.7 percent) which were unilateral.

The researchers found that there was no statistical difference in the number of biochemical or ongoing pregnancies in patients who had endometriomas and those who didn't. They also found that there was no difference in response to gonadotropin stimulation in patients with unilateral endometriomas between the affected and the contralateral ovary.

"Therefore, in patients with known endometriosis, surgically removing endometriomas prior to initializing in vitro fertilization may not be justified," the authors conclude.

SRMAmerican Society for Reproductive MedicineDowden Health Media

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